Moderna COVID vaccine efficacy drops as trial subjects double
As number of patients has doubled from 95 to 196, Moderna has reported a drop in efficacy for its COVID-19 vaccine from 94.5 per cent to 94.1 per cent
- Nov 30, 2020,
- Updated Dec 5, 2020 4:36 PM IST
When Moderna revised the efficacy rate for its COVID-19 vaccine candidate, it wasn't an entirely unexpected development. The US-based pharmaceutical major announced on Monday said that its experimental coronavirus inoculation showed 94.1 per cent effectiveness, slightly lower than 94.5 per cent the company had claimed at the end of first interim analysis for the same jab. The underlying difference was the number of subjects in each analysis - the former had 196 patients, whereas the latter had only 95. Moderna's Phase 3 trial is being conducted with over 30,000 registrants.
Moderna said that its vaccine has been 100 per cent effective in 30 severe case of coronavirus infection. The company also claimed that its vaccine mRNA-1273 is generally well-tolerated and there are no serious safety concerns over the jab.
When Moderna revised the efficacy rate for its COVID-19 vaccine candidate, it wasn't an entirely unexpected development. The US-based pharmaceutical major announced on Monday said that its experimental coronavirus inoculation showed 94.1 per cent effectiveness, slightly lower than 94.5 per cent the company had claimed at the end of first interim analysis for the same jab. The underlying difference was the number of subjects in each analysis - the former had 196 patients, whereas the latter had only 95. Moderna's Phase 3 trial is being conducted with over 30,000 registrants.
Moderna said that its vaccine has been 100 per cent effective in 30 severe case of coronavirus infection. The company also claimed that its vaccine mRNA-1273 is generally well-tolerated and there are no serious safety concerns over the jab.