'Friends' star Matthew Perry's death linked to ketamine drug: What is it and why is it legal to use?
Produced by: Tarun Mishra Designed by: Manoj Kumar
'Friends' star Matthew Perry's death
The recent passing of 'Friends' star Matthew Perry has drawn attention to the drug ketamine, as the Los Angeles County medical examiner determined his cause of death to be the "acute effects" of the substance.
What is ketamine?
Ketamine is a legal medication primarily used as an anaesthetic. While generally safe under medical supervision, Matthew Perry's case highlights potential risks associated with the drug.
Matthew Perry's circumstances
According to a report by La Times, Matthew Perry was found dead in his hot tub on October 28, and the medical examiner concluded the death was accidental. However, high levels of ketamine in his blood, along with other factors like drowning and coronary artery disease, contributed to the unfortunate incident.
Ketamine infusion therapy
Matthew Perry had been undergoing ketamine infusion therapy for mental health purposes. However, his last known infusion occurred a week and a half before his death, and the medical examiner ruled out the possibility that the ketamine found in his system was from that session.
Off-label use for mental health
Ketamine, recognised for its anaesthetic properties, has gained popularity in treating depression and other mental health disorders. The Food and Drug Administration (FDA) approved a prescription version called Spravato in 2019 for treatment-resistant depression. However, ketamine is also being utilised beyond its approved uses to address psychological conditions such as post-traumatic stress disorder (PTSD).
Rapid antidepressant effects
Research indicates that ketamine, injected through a syringe, has rapid antidepressant effects compared to traditional antidepressants. Around 300 clinical trials have demonstrated its fast-acting nature, providing relief for days or weeks.
Rise of ketamine clinics
The number of ketamine clinics in the US has increased significantly in recent years, offering the drug for mental health treatment. However, Matthew Perry's case highlights the need for caution and proper medical supervision.
Safety in medical settings
Ketamine is generally considered safe when administered in a controlled medical setting. Side effects like dissociation are less concerning when supervised by healthcare professionals, ensuring patients' safety.
Recreational use risks
Some individuals use ketamine recreationally to experience euphoria or dissociation. At high doses, it can lead to immobilization and hallucinations, known as a 'K-hole', complicating breathing and increasing heart demands.
Ketamine overdose considerations
Ketamine overdose by itself is rare, but mixing it with other substances, such as alcohol or opioids, can pose risks. Individuals with underlying health conditions like high blood pressure or breathing problems are at higher risk, emphasizing the importance of responsible use and testing for contaminants.
