Countries leading the COVID vaccine race

PANORAMA

Countries leading the COVID vaccine race

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There is a huge rush among nations across the globe to immunise their citizens against coronavirus. There are 191 COVID-19 vaccines under development around the world right now, and 41 of them are under clinical evaluation, according to the World Health Organisation. Here is the country-wise list of vaccine that has reached phase 2/3 stage of human clinical trials:

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UNITED KINGDOMEuropean regulators will soon start review of COVID-19 vaccine front-runner AstraZeneca and its partner University of Oxford. The European Medicines Agency is expected to announce the "rolling review" as soon as this week. A "rolling review" avoids delays so that approval from the European Commission can be sought as quickly as possible.The University of Oxford and AstraZeneca PLC has developed the first vaccine candidate to start the final round of testing of the coronavirus vaccine. The British-Swedish pharmaceutical firm AstraZeneca aims to make two billion doses available worldwide and said one billion doses of the vaccine will be available this year.

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The UNITED STATES
Moderna: US biotech firm Moderna has clearly stated that it will not be ready to apply for emergency authorisation for its COVID-19 vaccine before the US presidential election.Pfizer: Another US vaccine developer, Pfizer and its partner BioNTech have said the companies expect phase 3 data by the end of October. Novavax: The US-based biotech company will enroll 10,000 participants aged 18 to 84 within the next four to six weeks, with 25 per cent being over 65. Novavax is making a vaccine that consists of two shots given 21 days apartJohnson & Johnson: Another US-based frontrunner of COVID-19 vaccine J&J released an interim analysis from the ongoing phase 1/2 clinical trial of its candidate. The company said, "strong neutralising antibody response in nearly all participants were observed".

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RUSSIAThe chief executive officer of a Russian fertiliser company volunteered to take the Sputnik V vaccine and said he did not feel any side effects. Several other Russian billionaires chose to take the "made in Russia" COVID-19 vaccine, including, President Vladimir Putin's daughter, Industry Minister Denis Manturov, and Moscow Mayor Sergey Sobyanin.Sputnik V is developed by the Moscow-based Gamaleya Institute and is backed by the Russian Direct Investment Fund. It's still in a three-phase clinical trial. However, the institute has been giving shots to prominent people outside the trial groups for months without waiting for results from the full study.

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INDIAAccording to the Indian Council of Medical Research (ICMR), there are three COVID-19 vaccines under human trials--Bharat Biotech's COVAXIN, Oxford's COVDSHIELD, and Zydus Cadila's ZyCoV-D. Serum Institute has already begun a phase-3 trial of Oxford vaccine candidates at 17 sites, whereas Zydus Cadila and Bharat Biotech are conducting phase 2/3 trails.

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CHINAThere are three Chinese firms that have entered into the phase-3 clinical trials of the coronavirus vaccine. However, reports have surfaced that thousands of people in China have been given vaccine shots before the final regulatory approval for general use.China's biotechnology firm Sinopharm is developing two coronavirus vaccines with the government agencies Wuhan Institute of Biological Products and Beijing Institute of Biological Products.Another one is Sinovac which has also struck a deal with an Indonesian pharmaceutical firm called PT Bio farma to make up to 250 million vaccine doses each year for Indonesians.Sinopharm has given the vaccine to 350,000 people outside its clinical trials, whereas Sinovac has injected 90 per cent of its employees and family members or about 3,000 people.Separately, the Chinese military has approved the use of a vaccine it developed with CanSino Biologics Inc, a biopharmaceutical company, in military personnel.